Description

Lovastatin Hydroxy Acid, Sodium Salt is the water-soluble sodium salt form of the active metabolite of Lovastatin, a well-known statin. This form is critical for enhancing bioavailability and facilitating formulation in aqueous-based pharmaceutical systems. It is primarily utilized by manufacturers in the pharmaceutical and biotechnology sectors for the research, development, and production of cholesterol-lowering medications and related therapeutic agents.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of cholesterol-lowering drugs.
• Reference Standard in analytical laboratories for quality control and method validation.
• Biochemical Research for studying HMG-CoA reductase inhibition and lipid metabolism pathways.
• Pharmaceutical Intermediates in the synthesis of more complex statin derivatives.
• Preclinical & Clinical Development of new cardiovascular therapeutics.
• Cell Culture Studies investigating the effects of statins on cellular function.

Basic Information

Product Name	Lovastatin Hydroxy Acid, Sodium Salt
CAS No.	75225-51-3
Molecular Formula	C24H35NaO6
Molecular Weight	442.53 g/mol
Synonyms	Monacolin L Sodium Salt; L-154,819 Sodium Salt; (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl (2S)-2-methylbutanoate Hydroxy Acid Sodium Salt; Lovastatin Sodium Salt; Lovastatin Acid Sodium Salt; Sodium (3R,5R)-7-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate
EINECS	Contact for details

Quality Control

Our Lovastatin Hydroxy Acid, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with relevant in-house standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.