Description

Crilvastatin is a synthetic organic compound belonging to the statin class, known for its role as a key pharmaceutical intermediate. Its primary value lies in enabling the synthesis of advanced active pharmaceutical ingredients (APIs) for cholesterol management therapies. This high-purity intermediate is essential for manufacturers in the pharmaceutical and fine chemical industries requiring reliable, specification-grade building blocks for research and production.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of HMG-CoA reductase inhibitor (statin) APIs.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry for developing new cardiovascular drugs.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for creating complex molecular structures in a controlled GMP environment.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished dosage forms.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and impurity profiling via HPLC and other techniques.

Basic Information

Product Name	Crilvastatin
CAS No.	120551-59-9
Molecular Formula	C23H34FNO4
Molecular Weight	407.52 g/mol
Synonyms	(3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic Acid; (E)-(3R,5S)-7-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic Acid; Crilvastatin Intermediate; NSC 339531; Statin Intermediate
EINECS	Contact for details

Quality Control

Our Crilvastatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect the material from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.