Description

10-Octadecylacridine Orange Bromide is a cationic, lipophilic dye derivative of acridine orange, designed for enhanced membrane affinity and staining. This compound is valued for its ability to act as a fluorescent probe and photosensitizer in advanced research and diagnostic applications. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and material science sectors for studying cellular structures, developing assays, and investigating photodynamic processes.

Application

• Fluorescent Staining Agent: Used as a selective stain for nucleic acids, acidic organelles (e.g., lysosomes), and biomembranes in fluorescence microscopy and flow cytometry.
• Photosensitizer in Photodynamic Research: Investigated for its potential in photodynamic therapy (PDT) studies due to its light-activated properties for generating reactive oxygen species.
• Biophysical Probe: Employed in membrane biophysics to study lipid bilayer dynamics, membrane potential, and vesicle trafficking due to its long alkyl chain promoting integration.
• Diagnostic Reagent Development: Serves as a key component in developing fluorescent assays and kits for cell viability, apoptosis detection, and organelle labeling.
• Material Science Marker: Used to label and track polymeric nanoparticles, liposomes, and other drug delivery systems in formulation research.
• Research Chemical: A vital tool in academic and industrial R&D for exploring new applications in bioimaging and photochemistry.

Basic Information

Product Name	10-Octadecylacridine Orange Bromide
CAS No.	75168-16-0
Molecular Formula	C41H58BrN3
Molecular Weight	672.83 g/mol
Synonyms	N-Octadecyl Acridine Orange; Octadecyl Acridine Orange Bromide; Acridine Orange C18; 3,6-Bis(dimethylamino)acridine octadecyl bromide; N-Octadecyl-3,6-bis(dimethylamino)acridinium bromide; AO-C18; Lipophilic Acridine Orange; Acridine Orange long-chain alkyl derivative
EINECS	Contact for details

Quality Control

Our 10-Octadecylacridine Orange Bromide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and spectrophotometry for performance validation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, consider storage under an inert atmosphere. Keep the container tightly sealed in a desiccated environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Orange to red-orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Fluorescence Properties	Ex/Em: ~490/525 nm (in buffer, typical)
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.