Description

4-(6-Amino-3-Fluoro-2-Pyridyl)-1-Piperazinecarboxylic Acid Ethyl Ester is a high-value, fluorinated piperazine-pyridine derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a protected piperazine nitrogen and a reactive amino-fluoropyridine moiety, makes it an essential intermediate for constructing complex pharmacophores. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the fluoropyridine unit enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific electronic or binding properties.

Basic Information

Item	Details
Product Name	4-(6-Amino-3-Fluoro-2-Pyridyl)-1-Piperazinecarboxylic Acid Ethyl Ester
CAS No.	75167-28-1
Molecular Formula	C12H17FN4O2
Molecular Weight	268.29 g/mol
Synonyms	Ethyl 4-(6-Amino-3-fluoro-2-pyridinyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(6-amino-3-fluoro-2-pyridinyl)-, ethyl ester; 4-(6-Amino-3-fluoropyridin-2-yl)piperazine-1-carboxylic acid ethyl ester; 75167-28-1; 4-(6-Amino-3-fluoro-2-pyridyl)piperazine-1-carboxylic acid ethyl ester; Ethyl 4-(6-amino-3-fluoropyridin-2-yl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 4-(6-Amino-3-Fluoro-2-Pyridyl)-1-Piperazinecarboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in GMP-oriented research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.