Description

1,2-o-Isopropylidene-5-o-(4-Methylbenzoyl)-α-D-Xylofuranose is a key chiral intermediate and protected sugar derivative of significant importance in synthetic organic chemistry. Its primary value lies in its role as a versatile building block for the synthesis of nucleoside analogs, antiviral agents, and other biologically active compounds. This high-purity chemical is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Antiviral Drug Research: Used in the development and production of experimental antiviral compounds, leveraging its protected xylofuranose scaffold.
• Carbohydrate Chemistry: Serves as a protected precursor for the preparation of complex oligosaccharides, glycoconjugates, and other sugar-modified molecules.
• Fine Chemical Synthesis: Employed as a chiral synthon in asymmetric synthesis to introduce stereochemical complexity into target molecules.
• Process Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring a xylofuranose core structure.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and methodological studies in organic synthesis.

Basic Information

Product Name	1,2-o-Isopropylidene-5-o-(4-Methylbenzoyl)-α-D-Xylofuranose
CAS No.	75096-60-5
Molecular Formula	C16H20O6
Molecular Weight	308.33 g/mol
Synonyms	5-O-(4-Methylbenzoyl)-1,2-O-isopropylidene-α-D-xylofuranose; 1,2-O-Isopropylidene-5-O-p-toluoyl-α-D-xylofuranose; 5-O-p-Toluoyl-1,2-O-isopropylidene-α-D-xylofuranose; α-D-Xylofuranose, 1,2-O-(1-methylethylidene)-5-O-(4-methylbenzoyl)-; 1,2-O-Isopropylidene-α-D-xylofuranose 5-(4-methylbenzoate); Protected D-Xylofuranose Derivative
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-5-o-(4-Methylbenzoyl)-α-D-Xylofuranose is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality systems support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.