Description

4-Iodo-1-Methyl-1H-Pyrazole-5-Carboxylic Acid Methyl Ester is a high-value, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and an ester group, makes it an exceptionally versatile intermediate for constructing complex heterocyclic frameworks. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients through cross-coupling reactions and further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to create complex molecular architectures.
• Chemical Biology & Proteomics: Utilized as a tagging or labeling reagent in probe development for studying biological pathways and protein interactions.
• Ligand Synthesis: Acts as a starting material for creating novel chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Iodo-1-Methyl-1H-Pyrazole-5-Carboxylic Acid Methyl Ester
CAS No.	75092-26-1
Molecular Formula	C6H7IN2O2
Molecular Weight	266.04 g/mol
Synonyms	Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate; 1-Methyl-4-iodo-1H-pyrazole-5-carboxylic acid methyl ester; 4-Iodo-1-methylpyrazole-5-carboxylic acid methyl ester; 5-Carbomethoxy-1-methyl-4-iodopyrazole; 75092-26-1; 4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid, methyl ester; Methyl 1-methyl-4-iodo-1H-pyrazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of 4-Iodo-1-Methyl-1H-Pyrazole-5-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.