Description

Ethyl 2-(4-Nitrophenylthio)Acetate is a specialized organic sulfur compound featuring a nitro-substituted aromatic thioether moiety. This chemical serves as a valuable synthetic intermediate, enabling the introduction of the 4-nitrophenylthio functional group into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic frameworks. The compound's structure makes it a versatile building block for constructing molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the nitrophenylthio group is a critical pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the sulfur and nitro functionalities can contribute to biological activity.
• Organic Synthesis Reagent: Acts as an electrophile or a precursor for generating thiolate anions in nucleophilic substitution reactions to form carbon-sulfur bonds.
• Material Science Precursor: Potential starting material for the synthesis of functionalized polymers or ligands for metal-organic frameworks (MOFs) with specific electronic properties.
• Chemical Biology Probe Development: Useful for creating activity-based probes or affinity labels to study protein function and enzyme mechanisms in biochemical research.

Basic Information

Product Name	Ethyl 2-(4-Nitrophenylthio)Acetate
CAS No.	75032-27-8
Molecular Formula	C10H11NO4S
Molecular Weight	241.26 g/mol
Synonyms	Ethyl (4-Nitrophenylthio)acetate; Acetic acid, 2-[(4-nitrophenyl)thio]-, ethyl ester; Ethyl (p-Nitrophenylthio)acetate; 2-[(4-Nitrophenyl)sulfanyl]acetic acid ethyl ester; 4-Nitrophenylthioacetic acid ethyl ester; Ethyl 4-nitrophenylthioacetate; NSC 403796
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Nitrophenylthio)Acetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.