Description

2-Oxo-A-Norcholestane-3α-Carboxylic Acid Methyl Ester is a high-purity, specialized steroid derivative used as a critical intermediate in advanced organic synthesis. This compound is valued for its defined molecular architecture, which serves as a key building block in the research and development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on steroid chemistry, hormone-related therapies, and complex natural product synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor interactions, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a sophisticated building block for the multi-step synthesis of complex natural products and specialized chiral compounds.
• Biochemical Research: Employed as a standard or probe in biochemical assays related to endocrine function and metabolic pathways.
• Process Chemistry: Utilized in scaling up synthetic routes for potential drug candidates during process development and optimization phases.

Basic Information

Product Name	2-Oxo-A-Norcholestane-3α-Carboxylic Acid Methyl Ester
CAS No.	75023-18-6
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	Methyl 3α-Hydroxy-2-oxo-5β-cholan-24-oate; 3α-Hydroxy-2-oxo-5β-cholan-24-oic Acid Methyl Ester; 2-Oxo-5β-cholan-24-oic Acid, 3α-Hydroxy-, Methyl Ester; Methyl 3α-hydroxy-2-oxocholan-24-oate; A-Norcholestane-3α-carboxylic Acid, 2-Oxo-, Methyl Ester; 5β-Cholan-24-oic Acid, 3α-Hydroxy-2-oxo-, Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-Oxo-A-Norcholestane-3α-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.