Description

o-Tolyl-Carbamic Acid tert-Butyl Ester is a specialized organic compound belonging to the carbamate ester class. This chemical serves as a crucial building block and protected intermediate in advanced organic synthesis, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a protected amine functionality.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the o-tolyl moiety is integral.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the tert-butoxycarbonyl (Boc) protecting group to amines in complex multi-step syntheses.
• Peptide Chemistry: Employed in the preparation of amino acid derivatives and peptide fragments where temporary amine protection is required.
• Material Science Research: Potential monomer or modifier in the development of specialized polymers with tailored properties.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	o-Tolyl-Carbamic Acid tert-Butyl Ester
CAS No.	74965-31-4
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	tert-Butyl (2-methylphenyl)carbamate; N-(2-Methylphenyl)carbamic Acid tert-Butyl Ester; 2-Methylphenylcarbamic Acid tert-Butyl Ester; o-Tolylcarbamic Acid tert-Butyl Ester; Boc-o-toluidine; N-Boc-2-methylaniline; N-tert-Butoxycarbonyl-2-methylaniline; (2-Methylphenyl)carbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our o-Tolyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.