Description

Methyl 2,3-o-Carbonyl-4,6-o-Isopropylidene-A-D-Mannopyranoside is a key protected carbohydrate intermediate, specifically a mannose derivative with strategically blocked hydroxyl groups. This compound is essential for enabling selective chemical transformations in complex organic synthesis, ensuring high regioselectivity and yield. It is primarily required by pharmaceutical and fine chemical research laboratories for the development of glycosylated drugs, complex oligosaccharides, and advanced chiral building blocks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside analogs, antiviral agents, and other glycosylated active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Serves as a protected mannosyl donor or acceptor for constructing complex oligosaccharides and glycoconjugates in carbohydrate chemistry.
• Chiral Pool Synthesis: Utilized as a versatile chiral starting material for the asymmetric synthesis of natural products and specialty chemicals.
• Bioconjugate Chemistry: Used in the preparation of labeled sugars, glycopolymers, and carbohydrate-based probes for biochemical studies.
• Process Development: Employed in route scouting and scale-up processes for the manufacture of high-value fine chemicals under GMP conditions.

Basic Information

Product Name	Methyl 2,3-o-Carbonyl-4,6-o-Isopropylidene-A-D-Mannopyranoside
CAS No.	74948-73-5
Molecular Formula	C12H16O7
Molecular Weight	272.25 g/mol
Synonyms	Methyl 2,3-O-Carbonyl-4,6-O-Isopropylidene-α-D-Mannopyranoside; Methyl 4,6-O-Isopropylidene-2,3-O-carbonyl-α-D-mannopyranoside; 1-O-Methyl-4,6-O-isopropylidene-2,3-O-carbonyl-α-D-mannopyranoside; α-D-Mannopyranoside, methyl 2,3-O-carbonyl-4,6-O-(1-methylethylidene)-; Methyl 2,3-carbonyl-4,6-isopropylidene-α-D-mannoside; Protected Methyl α-D-Mannoside
EINECS	Contact for details

Quality Control

Our Methyl 2,3-o-Carbonyl-4,6-o-Isopropylidene-A-D-Mannopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.