Description

5-(Methoxycarbonyl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylic Acid is a high-purity, synthetically valuable dihydropyridine derivative. This compound serves as a critical advanced intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly within the cardiovascular therapeutic area. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and academic institutions engaged in medicinal chemistry and process development. The CAS number for this compound is 74936-72-4.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of calcium channel blockers and other dihydropyridine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes under GMP or non-GMP conditions.
• Academic & Institutional Research: Fundamental compound for studying the chemistry and pharmacology of 1,4-dihydropyridines.
• Fine Chemical Synthesis: Intermediate for creating specialized, high-value chemicals with specific nitrophenyl and ester functionalities.

Basic Information

Product Name	5-(Methoxycarbonyl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylic Acid
CAS No.	74936-72-4
Molecular Formula	C17H18N2O6
Molecular Weight	346.34 g/mol
Synonyms	3-Carboxy-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine; Methyl 3-Carboxy-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate; 4-(3-Nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3-carboxylic acid 5-methyl ester; 3-Carboxy-5-methoxycarbonyl-2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine; 1,4-DHP-3-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 5-(Methoxycarbonyl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.