Description

Propanoic Acid, 2-Methyl-3-(Phenylmethoxy)-, Methyl Ester, (S)- is a high-purity, single-enantiomer chiral building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, where stereochemical purity is critical for efficacy and safety. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereoselectivity.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides, where the specific (S)-configuration can influence biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of other high-value, optically active specialty chemicals and flavors & fragrances.
• Academic and Industrial Research: A valuable tool for chemists in universities and corporate R&D centers exploring new synthetic methodologies and reaction pathways.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial production for target molecules.

Basic Information

Product Name	Propanoic Acid, 2-Methyl-3-(Phenylmethoxy)-, Methyl Ester, (S)-
CAS No.	74924-27-9
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	(S)-Methyl 2-Methyl-3-(benzyloxy)propanoate; (S)-Methyl 3-(Benzyloxy)-2-methylpropanoate; (S)-3-(Benzyloxy)-2-methylpropionic Acid Methyl Ester; Methyl (S)-3-Benzyloxy-2-methylpropionate; (S)-(-)-Methyl 3-Benzyloxy-2-methylpropanoate; (S)-Homoalanine Derivative; BEMP Ester Intermediate; Chiral Propanoate Ester
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-Methyl-3-(Phenylmethoxy)-, Methyl Ester, (S)- is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (ee), and impurity profile. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.