Description

α-Interferon is a potent cytokine belonging to the type I interferon family, recognized for its critical role in modulating the immune system's antiviral and antiproliferative responses. This high-purity biological agent is essential for advanced therapeutic and research applications where precise biological activity and stringent quality are paramount. It is primarily utilized by the biopharmaceutical industry for drug development and by research institutions conducting immunological and oncological studies.

Application

• Therapeutic Drug Substance: Serves as the active pharmaceutical ingredient (API) in the formulation of antiviral and anticancer biologics.
• Clinical Research: Used in studies investigating immune response modulation, viral infection mechanisms, and cancer immunotherapy.
• In Vitro Diagnostics: Employed as a critical component in immunoassays and cell-based assays to study interferon signaling pathways.
• Biopharmaceutical Development: Acts as a reference standard and a key reagent in the development and quality control of biosimilar and novel biologic products.
• Cell Culture & Virology: Used to treat cell cultures to induce an antiviral state or to study host-pathogen interactions.

Basic Information

Product Name	α-Interferon
CAS No.	74899-72-2
Molecular Formula	C860H1353N227O255S9
Molecular Weight	Approx. 19,400 Da
Synonyms	IFN-α; Interferon alfa; Leukocyte Interferon; IFN-alpha; Roferon-A (brand name); Intron A (brand name); Interferon α-2; Interferon, leukocyte
EINECS	Contact for details

Quality Control

Our α-Interferon is manufactured and tested under a quality management system designed for biopharmaceutical actives. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, aligning with ICH Q6B guidelines for biotechnology products. A detailed Certificate of Analysis (COA) documenting purity by HPLC, specific activity, endotoxin levels, and sterility is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to prevent loss of activity. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (RP-HPLC)	≥ 98.0%
Specific Activity	≥ 2.0 x 108 IU/mg
Endotoxin	< 1.0 EU/mg
Protein Content (UV)	Conforms
Sterility (Membrane Filtration)	Sterile
Moisture Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.