Description

Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate is a high-purity chiral piperidine derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate stereochemically defined piperidine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Asymmetric Catalysis: Used as a precursor for chiral ligands or catalysts in stereoselective chemical transformations.
• Agrochemical Research: Serves as a building block for developing novel, optically active pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate
CAS No.	74892-82-3
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl (2R,4R)-4-methylpiperidine-2-carboxylate; (2R,4R)-4-Methyl-2-piperidinecarboxylic acid ethyl ester; (2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate; (2R,4R)-rel-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-methyl-2-piperidinecarboxylate (stereoisomer); UNII-8Q2Q8F4W6F; 74892-82-3; 4-Methyl-2-piperidinecarboxylic acid, ethyl ester, (2R,4R)-
EINECS	Contact for details

Quality Control

Our Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.