Description

Rel-Ethylmethyl[[(1S*)-5β*-Methyl-2α*-(1-Methylethyl)Cyclohexane-1α*-Yl]Oxy]Phenylsilane is a specialized organosilicon compound with a complex, sterically hindered structure. This compound is valued for its utility as a key intermediate or ligand in advanced synthetic chemistry, particularly in catalytic and asymmetric synthesis processes. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecules with high stereoselectivity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry.
• Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis, enabling asymmetric hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereoisomerically pure pesticides and herbicides.
• Fine Chemical Manufacturing: Acts as a sophisticated synthon for producing high-value specialty chemicals, flavors, and fragrances.
• Material Science Research: Investigated for potential use in modifying surface properties or creating novel silicon-based polymers and hybrid materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	Rel-Ethylmethyl[[(1S*)-5β*-Methyl-2α*-(1-Methylethyl)Cyclohexane-1α*-Yl]Oxy]Phenylsilane
CAS No.	74841-58-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ethylmethyl(phenoxy)[(1S,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexyl]silane (stereoisomer); Silane, ethylmethyl[[(1S,2R,5S)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]phenyl-; Ethylmethyl((1S,2R,5S)-5-methyl-2-isopropylcyclohexyloxy)phenylsilane; [(1S,2R,5S)-5-Methyl-2-(propan-2-yl)cyclohexyl]oxy(ethyl)methyl(phenyl)silane; Rel-((1S,2R,5S)-5-Methyl-2-isopropylcyclohexyloxy)ethylmethylphenylsilane; Sterically hindered phenoxysilane derivative; Chiral cyclohexyloxy silane intermediate.
EINECS	Contact for details

Quality Control

Every batch of Rel-Ethylmethyl[[(1S*)-5β*-Methyl-2α*-(1-Methylethyl)Cyclohexane-1α*-Yl]Oxy]Phenylsilane is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing, including chiral purity analysis and impurity profiling, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), and stereochemical composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.