Description

2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Trichloroacetimidate is a high-purity glycosyl donor, a critical building block in synthetic organic chemistry. Its primary value lies in enabling efficient and stereoselective glycosylation reactions, which are fundamental for constructing complex carbohydrate structures. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly for the synthesis of oligosaccharides, glycoconjugates, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of complex carbohydrate-based drugs, including antibiotics, antivirals, and anticancer agents.
• Oligosaccharide Synthesis: Enables the precise, stepwise construction of specific oligosaccharide chains for research and diagnostic applications.
• Glycoconjugate Production: Used in creating glycoproteins, glycolipids, and other conjugates for vaccine development and biochemical studies.
• Glycoscience Research: A fundamental tool in academic and industrial laboratories for studying glycosylation mechanisms and carbohydrate-protein interactions.
• Fine Chemical Synthesis: Serves as a specialized intermediate in the production of high-value chiral compounds and flavors.
• Process Development: Employed in scaling up glycosylation steps for the commercial manufacturing of carbohydrate-active ingredients.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Trichloroacetimidate
CAS No.	74808-10-9
Molecular Formula	C14H18Cl3NO9
Molecular Weight	466.65 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl trichloroacetimidate; α-D-Glucopyranose, 2,3,4,6-tetraacetate, 1-[2,2,2-trichloroethanimidate]; Trichloroacetimidic Acid 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Ester; Ac4Glcα-Trichloroacetimidate; Glc(Ac)4-α-TCA; Glycosyl Donor TCA; 1-O-Trichloroacetimidoyl-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Trichloroacetimidate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure high chemical purity and correct stereochemical configuration. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+80.0° to +85.0° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.