Description

4-Chloro-2-[(2-Furylmethyl)Amino]-5-[[(Trimethylsilyl)Amino]Sulfonyl]Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonamide and silyl-protected amine functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development programs targeting new therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those requiring a sulfonamide pharmacophore.
• Agrochemical Research: Used in the development of new herbicides or fungicides where the chlorinated benzoic acid ester moiety is active.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or probes used in biochemical and cellular studies.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs offering bespoke chemical manufacturing services.

Basic Information

Product Name	4-Chloro-2-[(2-Furylmethyl)Amino]-5-[[(Trimethylsilyl)Amino]Sulfonyl]Benzoic Acid Methyl Ester
CAS No.	74793-84-3
Molecular Formula	C16H21ClN2O5SSi
Molecular Weight	416.96 g/mol
Synonyms	Methyl 4-Chloro-2-[(furan-2-ylmethyl)amino]-5-[(trimethylsilylamino)sulfonyl]benzoate; Benzoic acid, 4-chloro-2-[(2-furanylmethyl)amino]-5-[[(trimethylsilyl)amino]sulfonyl]-, methyl ester; 4-Chloro-2-[(2-furylmethyl)amino]-5-{[(trimethylsilyl)amino]sulfonyl}benzoic acid methyl ester; TMS-protected sulfonamide benzoate ester; 74793-84-3
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-[(2-Furylmethyl)Amino]-5-[[(Trimethylsilyl)Amino]Sulfonyl]Benzoic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and compliance for advanced R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.