Description

4-Butyl-2-Phenyl-5-[(Trimethylsilyl)Oxy]-1-[4-[(Trimethylsilyl)Oxy]Phenyl]-1H-Pyrazol-3(2H)-One is a specialized, high-value organosilicon pyrazolone derivative designed for advanced synthetic chemistry applications. This compound is critical for researchers and manufacturers requiring precise, protected intermediates to build complex molecular architectures. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and advanced materials, where its unique silyl-protected functional groups offer superior control over reaction pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting inflammation or central nervous system disorders.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging its pyrazolone core for biological activity.
• Material Science Precursor: Acts as a monomer or functional additive in the creation of specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis Reagent: Employed in complex multi-step syntheses, where its trimethylsilyl (TMS) protecting groups are essential for selective reactions.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting for new chemical entities.
• Dye & Pigment Intermediate: Potential use in the synthesis of high-performance organic colorants and functional dyes due to its conjugated structure.

Basic Information

Product Name	4-Butyl-2-Phenyl-5-[(Trimethylsilyl)Oxy]-1-[4-[(Trimethylsilyl)Oxy]Phenyl]-1H-Pyrazol-3(2H)-One
CAS No.	74793-81-0
Molecular Formula	C27H38N2O3Si2
Molecular Weight	494.78 g/mol
Synonyms	1H-Pyrazol-3(2H)-one, 4-butyl-2-phenyl-5-[(trimethylsilyl)oxy]-1-[4-[(trimethylsilyl)oxy]phenyl]-; 4-Butyl-2-phenyl-5-(trimethylsiloxy)-1-[4-(trimethylsiloxy)phenyl]-1H-pyrazol-3(2H)-one; 5-Hydroxy-4-butyl-2-phenyl-1-[4-hydroxyphenyl]-1H-pyrazol-3(2H)-one bis(trimethylsilyl) ether; Pyrazolone TMS ether derivative; Bis-TMS-protected pyrazolone; CAS 74793-81-0
EINECS	Contact for details

Quality Control

Our production of 4-Butyl-2-Phenyl-5-[(Trimethylsilyl)Oxy]-1-[4-[(Trimethylsilyl)Oxy]Phenyl]-1H-Pyrazol-3(2H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate in compliance with cGMP principles where applicable, supporting our commitment to supplying reliable, research-grade intermediates for critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.