Description

(2R,3S)-1,2,3,4-Butanetetrol 1,4-Dibenzoate is a high-purity, stereochemically defined derivative of butanetetrol (erythritol) where the primary hydroxyl groups are esterified with benzoic acid. This specific enantiomer is valued for its role as a key chiral intermediate and building block in advanced organic synthesis, offering precise molecular geometry critical for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced material sectors who require high-fidelity chiral precursors to ensure the efficacy and specificity of their final products.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A critical building block for the asymmetric synthesis of complex drug molecules, particularly in developing nucleoside analogs and other bioactive compounds.
• Agrochemical Research & Development: Used in the creation of enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity and environmental safety.
• Liquid Crystal & Advanced Material Precursor: Serves as a foundational unit in synthesizing chiral dopants and monomers for liquid crystal displays (LCDs) and polymers with specific optical properties.
• Asymmetric Catalyst Ligand Synthesis: Employed in the preparation of sophisticated ligand systems for metal-catalyzed reactions requiring high enantioselectivity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for probing structure-activity relationships (SAR).
• Fine Chemical Production: Utilized in the manufacture of specialty esters, flavors, and fragrances where the defined stereochemistry of the butanetetrol core is advantageous.

Basic Information

Item	Detail
Product Name	(2R,3S)-1,2,3,4-Butanetetrol 1,4-Dibenzoate
CAS No.	74793-33-2
Molecular Formula	C18H18O6
Molecular Weight	330.33 g/mol
Synonyms	(2R,3S)-1,2,3,4-Butanetetrol 1,4-Dibenzoate; (2R,3S)-Erythritol 1,4-Dibenzoate; 1,4-Di-O-benzoyl-(2R,3S)-erythritol; (2R,3S)-1,2,3,4-Tetrahydroxybutane 1,4-Dibenzoate; D-erythro-1,2,3,4-Butanetetrol 1,4-Dibenzoate; (2R,3S)-Tetrahydroxybutane Dibenzoate; CAS 74793-33-2
EINECS	Contact for details

Quality Control

Every batch of (2R,3S)-1,2,3,4-Butanetetrol 1,4-Dibenzoate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. Our quality system is designed to support cGMP and ISO standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is moisture-sensitive (hygroscopic); keep the container tightly sealed to prevent absorption of water vapor from the atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Specific range available on request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Specific Rotation	Reported value per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.