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2,2,9,9-Tetramethyl-5,6-Bis[[(Trimethylsilyl)Oxy]Methyl]-3,8-Dioxa-2,9-Disiladecane CAS NO 74779-61-6


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CAS No.:74779-61-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,2,9,9-Tetramethyl-5,6-Bis[[(Trimethylsilyl)Oxy]Methyl]-3,8-Dioxa-2,9-Disiladecane is a specialized organosilicon compound that serves as a versatile protecting group reagent and synthetic intermediate in advanced organic synthesis. Its value lies in its ability to protect sensitive hydroxyl functionalities under demanding reaction conditions, enabling complex multi-step syntheses. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for developing active ingredients and novel polymers.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly for protecting hydroxyl groups during peptide and nucleoside chemistry.
  • Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides and herbicides where selective protection is required.
  • Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty silicones and silicon-containing polymers with tailored properties.
  • Organic Synthesis Reagent: Employed as a protecting group for diols and polyols in multi-step synthetic routes for natural products and fine chemicals.
  • Surface Modification: Utilized to introduce silyl ether groups onto material surfaces, altering hydrophobicity and reactivity.
  • Chemical Research: A valuable tool in academic and industrial R&D for methodology development and exploring new reaction pathways.

Basic Information

Product Name 2,2,9,9-Tetramethyl-5,6-Bis[[(Trimethylsilyl)Oxy]Methyl]-3,8-Dioxa-2,9-Disiladecane
CAS No. 74779-61-6
Molecular Formula C16H40O4Si4
Molecular Weight 424.86 g/mol
Synonyms 1,2-Bis[(tert-butyldimethylsilyloxy)methyl]-1,2-bis(trimethylsilyloxy)ethane; 1,2-Bis-O-(tert-butyldimethylsilyl)-1,2-bis-O-(trimethylsilyl)-1,2-ethanediol; TBDMS/TMS Protected Ethylene Glycol; 1,2-Ethanediol, 1,2-bis[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2-bis[(trimethylsilyl)oxy]-; 1,2-Bis(tert-butyldimethylsilyloxy)-1,2-bis(trimethylsilyloxy)ethane; Bis(protected) Ethylene Glycol Derivative
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Quality Control

Our 2,2,9,9-Tetramethyl-5,6-Bis[[(Trimethylsilyl)Oxy]Methyl]-3,8-Dioxa-2,9-Disiladecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC/HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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