Description

.Beta.-D-Gluco-Hexodialdo-1,5-Pyranose, S-Phenyl Monothiohemiacetal, Pentaacetate is a specialized, high-purity carbohydrate derivative used as a critical synthetic intermediate. This compound matters for its role in the synthesis of complex thioglycosides and other bioactive molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced carbohydrate chemistry, medicinal chemistry, and the development of glycosidase inhibitors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thioglycoside-based drug candidates and prodrugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop enzyme inhibitors targeting glycosidases.
• Carbohydrate Chemistry: Serves as a protected, activated sugar donor for the stereoselective construction of S-linked oligosaccharides and glycoconjugates.
• Biochemical Tool Development: Utilized in the preparation of affinity probes and labeled substrates for studying carbohydrate-processing enzymes.
• Academic & Industrial R&D: Essential reagent for exploratory synthetic routes in organic and bioorganic chemistry laboratories.

Basic Information

Product Name	.Beta.-D-Gluco-Hexodialdo-1,5-Pyranose, S-Phenyl Monothiohemiacetal, Pentaacetate
CAS No.	74774-20-2
Molecular Formula	C25H28O11S
Molecular Weight	536.55 g/mol
Synonyms	1,2,3,4,6-Penta-O-acetyl-β-D-glucopyranose S-phenyl monothiohemiacetal; Penta-O-acetyl-β-D-glucopyranosyl phenyl sulfide (hemiacetal form); β-D-Glucopyranose, S-phenyl monothiohemiacetal, 1,2,3,4,6-pentaacetate; 1-Thio-β-D-glucopyranose pentaacetate, S-phenyl derivative; CAS 74774-20-2; β-D-Glucopyranosyl phenyl sulfide pentaacetate (hemiacetal); Phenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside (common misnomer for hemiacetal form).
EINECS	Contact for details

Quality Control

Our .Beta.-D-Gluco-Hexodialdo-1,5-Pyranose, S-Phenyl Monothiohemiacetal, Pentaacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Specification available upon request
Specific Rotation	Specification available upon request
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.