Description

5-(4-Fluoro-Phenyl)-4-Pyridin-3-Yl-1H-Imidazole-2-Thiol is a high-value, heterocyclic organic compound featuring a unique imidazole-thiol core substituted with fluorophenyl and pyridinyl groups. This specific molecular architecture makes it a critical pharmacophore and versatile synthetic intermediate for advanced research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies and biological pathway investigations.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Material Science: Investigated for use in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in organic chemistry for constructing complex heterocyclic systems and functionalized molecules.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-4-Pyridin-3-Yl-1H-Imidazole-2-Thiol
CAS No.	74767-75-2
Molecular Formula	C₁₄H₁₀FN₃S
Molecular Weight	271.31 g/mol
Synonyms	5-(4-Fluorophenyl)-4-(pyridin-3-yl)-1H-imidazole-2-thiol; 4-(3-Pyridinyl)-5-(4-fluorophenyl)-1H-imidazole-2-thiol; 2-Mercapto-5-(4-fluorophenyl)-4-(3-pyridinyl)imidazole; 74767-75-2; 5-(p-Fluorophenyl)-4-(3-pyridyl)-2-mercaptoimidazole
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluoro-Phenyl)-4-Pyridin-3-Yl-1H-Imidazole-2-Thiol adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. The final product is characterized and verified using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.