Description

α-Oxopyridine-4-Acetonitrile is a versatile pyridine-based nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a nitrile and a carbonyl group on the pyridine ring, makes it a critical intermediate for constructing complex heterocyclic systems. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing fused pyridine or pyridone scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic reactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its functional group diversity.
• Chemical Research & Development: A valuable building block for academic and industrial R&D focused on heterocyclic and medicinal chemistry.

Basic Information

Product Name	α-Oxopyridine-4-Acetonitrile
CAS No.	74764-66-2
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	4-Pyridylglyoxylonitrile; 2-Oxo-2-(4-pyridinyl)acetonitrile; 4-Pyridinylglyoxylonitrile; 4-Cyanopyruvoylpyridine; (4-Pyridinyl)-oxoacetonitrile; 4-Pyridineglyoxylonitrile; 2-(4-Pyridinyl)-2-oxoacetonitrile; α-Oxo-4-pyridineacetonitrile
EINECS	Contact for details

Quality Control

Our α-Oxopyridine-4-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.