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1-(2-Chloroethyl)-3-(3-Deoxy-1-o-Methyl-2,4,6-Tri-o-Acetyl-D-Glucopyra Nos-3-Yl)-1-Nitrosourea CAS NO 74751-37-4
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CAS No.:74751-37-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(2-Chloroethyl)-3-(3-Deoxy-1-o-Methyl-2,4,6-Tri-o-Acetyl-D-Glucopyra Nos-3-Yl)-1-Nitrosourea is a specialized nitrosourea derivative with a complex carbohydrate moiety, representing a high-value synthetic intermediate in advanced organic synthesis. Its molecular architecture makes it a critical building block for researchers developing novel bioactive compounds, particularly in targeted therapeutic areas. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating next-generation glycoconjugates and prodrugs.
Application
- Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel alkylating agents and targeted cancer therapeutics.
- Glycoconjugate Research: Used in the development of carbohydrate-based drug delivery systems and prodrugs due to its acetylated sugar component.
- Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies in the search for new enzyme inhibitors.
- Bioconjugation: Employed in the design of chemically modified biomolecules for diagnostic and therapeutic applications.
- Academic & Institutional R&D: Utilized in university and research institute laboratories for fundamental studies in organic and bioorganic chemistry.
- Fine Chemical Synthesis: Acts as a specialized reagent for introducing the nitrosourea pharmacophore into complex molecular architectures.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 1-(2-Chloroethyl)-3-(3-Deoxy-1-o-Methyl-2,4,6-Tri-o-Acetyl-D-Glucopyra Nos-3-Yl)-1-Nitrosourea |
| CAS No. | 74751-37-4 |
| Molecular Formula | C₁₈H₂₆ClN₃O₁₀ |
| Molecular Weight | 503.86 g/mol |
| Synonyms | 1-(2-Chloroethyl)-3-(3-deoxy-1-O-methyl-2,4,6-tri-O-acetyl-α-D-glucopyranos-3-yl)-1-nitrosourea; 3-Deoxy-1-O-methyl-2,4,6-tri-O-acetyl-α-D-glucopyranos-3-yl 1-(2-chloroethyl)-1-nitrosourea; Chloroethyl Nitrosourea Glucopyranoside Derivative; CNU-Glucoside Intermediate; Nitrosourea Glycoside |
| EINECS | Contact for details |
Quality Control
Our 1-(2-Chloroethyl)-3-(3-Deoxy-1-o-Methyl-2,4,6-Tri-o-Acetyl-D-Glucopyra Nos-3-Yl)-1-Nitrosourea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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