Description

1-(2-Chloroethyl)-3-(2,6-Dideoxy-1-O,3-O,4-o-Triacetyl-D-Glucopyranos-2-Yl)-1-Nitrosourea is a specialized nitrosourea derivative with a complex glycosylated structure, designed for targeted chemical and biological activity. This compound is of significant interest in advanced pharmaceutical research and development due to its potential as a precursor or active moiety in prodrug synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anticancer agents and targeted prodrugs.
• Biochemical Research: Used as a tool compound in studies investigating alkylating agent mechanisms and DNA interaction.
• Antitumor Agent Development: Acts as a key precursor for the development of glycosylated nitrosourea analogs designed for improved selectivity and reduced systemic toxicity.
• Prodrug Synthesis: Utilized in creating chemically activated prodrug systems that target specific enzymes or cellular environments.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and pharmacokinetic profile of nitrosourea-based therapeutics.
• Academic Research: Used in university and institutional labs for fundamental research on glycoside conjugation and drug design principles.

Basic Information

Product Name	1-(2-Chloroethyl)-3-(2,6-Dideoxy-1-O,3-O,4-o-Triacetyl-D-Glucopyranos-2-Yl)-1-Nitrosourea
CAS No.	74729-54-7
Molecular Formula	C₁₇H₂₄ClN₃O₉
Molecular Weight	449.84 g/mol
Synonyms	1-(2-Chloroethyl)-3-(2,6-dideoxy-1-O,3-O,4-O-triacetyl-α-D-glucopyranos-2-yl)-1-nitrosourea; 1-Nitrosourea, 1-(2-chloroethyl)-3-(2,6-dideoxy-1-O,3-O,4-O-triacetyl-α-D-glucopyranos-2-yl)-; Glycosylated CENU; Triacetylated Glucosyl Nitrosourea; Chloroethylnitrosourea Glycoside Derivative; NSC-Derivative 74729-54-7; α-D-Glucopyranoside derivative of nitrosourea
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-3-(2,6-Dideoxy-1-O,3-O,4-o-Triacetyl-D-Glucopyranos-2-Yl)-1-Nitrosourea is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support preclinical and early-phase pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is light-sensitive (store away from light). Keep the container tightly sealed in a cool, dry, and well-ventilated place. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.