Description

4-(Iodomethyl)Azetidin-2-One is a high-value, multi-functional azetidinone building block, crucial for advanced organic synthesis. Its reactive iodomethyl and β-lactam functionalities make it an indispensable intermediate for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel β-lactam antibiotics and other nitrogen-based bioactive molecules.
• Chemical Building Block: Used in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions to introduce functionalized azetidine rings into complex structures.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides with unique modes of action.
• Material Science: Potential monomer or modifier for creating polymers with specific thermal or mechanical properties.
• Academic & R&D: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-(Iodomethyl)Azetidin-2-One
CAS No.	74694-50-1
Molecular Formula	C4H6INO
Molecular Weight	210.00 g/mol
Synonyms	4-(Iodomethyl)azetidin-2-one; 1-Azaspiro[2.2]pentan-3-one, 4-(iodomethyl)-; 4-Iodomethyl-2-azetidinone; (Iodomethyl)azetidinone; Azetidin-2-one, 4-(iodomethyl)-; 4-(Iodomethyl)-2-azetidinone; β-lactam, 4-(iodomethyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-(Iodomethyl)Azetidin-2-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with customer specifications and current Good Manufacturing Practices (cGMP) where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.