Description

Arabino-Hexos-2-Ulose, 3,4,5,6-Tetrakis-o-(Trimethylsilyl)-, Bis(Dimethyl Acetal) is a sophisticated, fully protected carbohydrate derivative, specifically a silylated sugar acetal. This compound is engineered to provide exceptional stability and solubility in organic solvents, making it a critical advanced intermediate for complex synthetic pathways. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel nucleoside analogs, complex oligosaccharides, and other bioactive molecules where precise stereochemistry and functional group protection are paramount.

Application

• Advanced Pharmaceutical Intermediates: Key building block in the multi-step synthesis of novel antiviral or anticancer nucleoside drugs.
• Carbohydrate Chemistry Research: Serves as a protected precursor for the controlled construction of complex oligosaccharides and glycoconjugates.
• Glycomimetics Development: Used to create sugar analogs that mimic natural carbohydrates for drug discovery and biochemical studies.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the production of high-value specialty chemicals.
• Chemical Biology Probes: Facilitates the synthesis of labeled or modified sugars used to study biological recognition and metabolic pathways.
• Chiral Pool Synthesis: Provides a source of defined chirality for the asymmetric synthesis of non-carbohydrate targets.

Basic Information

Item	Detail
Product Name	Arabino-Hexos-2-Ulose, 3,4,5,6-Tetrakis-o-(Trimethylsilyl)-, Bis(Dimethyl Acetal)
CAS No.	74685-71-5
Molecular Formula	C24H56O8Si4
Molecular Weight	609.15 g/mol
Synonyms	3,4,5,6-Tetra-O-trimethylsilyl-D-arabino-hexos-2-ulose bis(dimethyl acetal); D-Arabino-Hexos-2-ulose, 3,4,5,6-tetrakis-O-(trimethylsilyl)-, dimethyl acetal; Protected Arabino-Hexosulose Acetal; TMS-protected Sugar Acetal; Silylated Hexosulose Derivative; CAS 74685-71-5
EINECS	Contact for details

Quality Control

Every batch of our Arabino-Hexos-2-Ulose derivative is produced and analyzed under strict quality protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity, and moisture content. Our quality system is designed to support cGMP-compliant research and development activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (argon or nitrogen) after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.