Description

(S)-2-Benzyloxycarbonylamino-3-Iodo-Propionic Acid Methyl Ester is a high-purity, chiral iodinated amino acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a protected, stereochemically defined building block for constructing complex peptide mimetics and biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel therapeutic agents and in sophisticated peptide synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce iodinated tyrosine or phenylalanine analogs with defined (S)-configuration.
• Chemical Biology Probes: Acts as a precursor for radiolabeling (e.g., with I-125) to create molecular probes for imaging and diagnostic applications.
• Organocatalyst & Ligand Synthesis: Serves as a starting material for synthesizing chiral ligands and catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Bioconjugation: The iodine atom offers a handle for further functionalization via cross-coupling reactions, useful in bioconjugation strategies.

Basic Information

Product Name	(S)-2-Benzyloxycarbonylamino-3-Iodo-Propionic Acid Methyl Ester
CAS No.	74683-70-8
Molecular Formula	C12H14INO4
Molecular Weight	363.15 g/mol
Synonyms	Methyl (S)-2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate; (S)-Methyl 2-((((benzyloxy)carbonyl)amino)-3-iodopropanoate; Z-Iodoalanine-OMe; (S)-Z-Iodoalanine Methyl Ester; (S)-2-(N-Cbz-Amino)-3-iodopropionic Acid Methyl Ester; (S)-N-Cbz-3-iodoalanine methyl ester; (S)-3-Iodo-2-((((benzyloxy)carbonyl)amino)propanoic acid methyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)-3-iodopropanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our (S)-2-Benzyloxycarbonylamino-3-Iodo-Propionic Acid Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical purity, and identity confirmation. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.