Description

n-((4-Azidophenyl)Thio)Phthalimide is a specialized organic compound featuring a reactive azide group and a phthalimide moiety, making it a valuable intermediate in advanced chemical synthesis. Its core value lies in its ability to participate in click chemistry reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling precise and efficient molecular assembly. This compound is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors who require high-purity building blocks for developing new drugs, polymers, and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring site-specific conjugation.
• Bioconjugation Reagent: Used for labeling proteins, antibodies, and other biomolecules with fluorescent dyes, drugs, or polymers via azide-based click chemistry.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent in the development of advanced polymers, hydrogels, and smart materials with tailored properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes for studying enzyme function and cellular processes.
• Agrochemical Synthesis: An intermediate in the research and development of new crop protection agents and herbicides.
• Surface Modification: Facilitates the functionalization of nanoparticles, chips, and other surfaces for biosensing and diagnostic applications.

Basic Information

Product Name	n-((4-Azidophenyl)Thio)Phthalimide
CAS No.	74676-97-4
Molecular Formula	C14H8N4O2S
Molecular Weight	296.30 g/mol
Synonyms	N-(4-Azidophenylthio)phthalimide; 1-[(4-Azidophenyl)sulfanyl]isoindole-1,3-dione; 4-Azidophenylsulfenyl Phthalimide; Phthalimide, N-((4-azidophenyl)thio)-; 4-Phthalimidosulfenyl azidobenzene; N-(p-Azidophenylthio)phthalimide; 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-ylsulfanyl)phenyl azide
EINECS	Contact for details

Quality Control

Our n-((4-Azidophenyl)Thio)Phthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications in GMP and research environments where reliable performance is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.