Description

2-Chloro-5-Hydroxypyridine-3-Carbonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, hydroxyl, and nitrile functional groups, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Acts as a monomer or functional unit in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of new chemical spaces and structure-activity relationships (SAR).

Basic Information

Product Name	2-Chloro-5-Hydroxypyridine-3-Carbonitrile
CAS No.	74650-75-2
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	3-Cyano-2-chloro-5-hydroxypyridine; 5-Hydroxy-2-chloronicotinonitrile; 2-Chloro-5-hydroxynicotinonitrile; 2-Chloro-5-pyridinol-3-carbonitrile; 74650-75-2; 2-Chloro-5-hydroxy-3-cyanopyridine; 5-Hydroxy-2-chloro-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Hydroxypyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.