Description

6'-Amino-3'-Methyl-2-Oxo-1'-Phenyl-1,2-Dihydro-1'H-Spiro[Indole-3,4'-Pyrano[2,3-C]Pyrazole]-5'-Carbonitrile is a high-purity, complex heterocyclic compound featuring a unique spirocyclic architecture. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile scaffold in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries due to its spiro[indole-pyranopyrazole] core.
• Organic Synthesis Reagent: Employed in the development of complex heterocyclic compounds for academic and industrial research.
• Agrochemical Research: Potential intermediate in the synthesis of new-generation pesticides and herbicides, leveraging its bioactive nitrogen-rich structure.
• Dye & Pigment Precursor: The amino and cyano functional groups make it a candidate for synthesizing specialized organic colorants and functional materials.

Basic Information

Item	Details
Product Name	6'-Amino-3'-Methyl-2-Oxo-1'-Phenyl-1,2-Dihydro-1'H-Spiro[Indole-3,4'-Pyrano[2,3-C]Pyrazole]-5'-Carbonitrile
CAS No.	74647-55-5
Molecular Formula	C21H15N5O2
Molecular Weight	369.38 g/mol
Synonyms	6'-Amino-3'-methyl-2-oxo-1'-phenyl-1,2-dihydrospiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile; 1'H-Spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile, 6'-amino-1,2-dihydro-3'-methyl-2-oxo-1'-phenyl-; Spiro[indole-3,4'-pyrano[2,3-c]pyrazole] derivative (CAS 74647-55-5); 6'-Amino-3'-methyl-1'-phenyl-1,2-dihydrospiro[indole-3,4'-pyrano[2,3-c]pyrazole]-2,5'(1'H)-dione-5'-carbonitrile (related tautomer); 74647-55-5; Amino-methyl-oxo-phenyl-spiro carbonitrile.
EINECS	Contact for details

Quality Control

Our 6'-Amino-3'-Methyl-2-Oxo-1'-Phenyl-1,2-Dihydro-1'H-Spiro[Indole-3,4'-Pyrano[2,3-C]Pyrazole]-5'-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.