Description

4-Azido-4-Deoxy-D-Glucose is a chemically modified monosaccharide derivative, specifically a deoxy sugar bearing an azido functional group at the C-4 position. This unique structure makes it a valuable biochemical tool and a versatile intermediate for click chemistry applications, enabling selective labeling and conjugation in complex biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel probes, glycoconjugates, and metabolic inhibitors.

Application

• Biochemical Probe Development: Acts as a metabolic precursor for labeling cell surface glycans via bioorthogonal click chemistry (e.g., with alkynes).
• Glycobiology Research: Used to study glucose metabolism, glycosylation pathways, and the function of specific sugar transporters in cells.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel antiviral or anticancer nucleoside analogs.
• Diagnostic Agent Synthesis: Employed in the creation of radiolabeled or fluorescent-tagged tracers for imaging applications.
• Material Science: Can be incorporated into polymers or surfaces to introduce biofunctional azido groups for further modification.
• Enzyme Inhibition Studies: Used to investigate and potentially inhibit specific glycosidases or kinases involved in disease pathways.

Basic Information

Product Name	4-Azido-4-Deoxy-D-Glucose
CAS No.	74593-35-4
Molecular Formula	C6H11N3O5
Molecular Weight	205.17 g/mol
Synonyms	4-Azido-4-deoxy-D-glucose; 4-Azido-4-deoxyglucose; 4-Azido-4-deoxy-D-glucopyranose; D-Glucose, 4-azido-4-deoxy-; 4-Deoxy-4-azido-D-glucose; Azidodeoxyglucose; 4-ADG
EINECS	Contact for details

Quality Control

Our 4-Azido-4-Deoxy-D-Glucose is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.