Description

Ethyl 2-[(1E)-Cyclopropylidene]Acetate is a versatile α,β-unsaturated ester building block featuring a reactive exocyclic double bond. This compound is valued for its unique cyclopropylidene moiety, which imparts significant synthetic utility in constructing complex molecular frameworks. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cyclopropanation reactions, Diels-Alder cycloadditions, and as a precursor for advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing strained ring systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that leverage the cyclopropane ring for biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, conjugate additions, and catalytic transformations to create complex organic molecules.
• Flavor & Fragrance Chemistry: Investigated as a potential intermediate for synthesizing esters with novel olfactory characteristics.

Basic Information

Product Name	Ethyl 2-[(1E)-Cyclopropylidene]Acetate
CAS No.	74592-36-2
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	Ethyl (1E)-2-Cyclopropylideneacetate; (E)-Ethyl 2-Cyclopropylideneacetate; Ethyl (E)-2-Cyclopropylideneacetate; 2-Cyclopropylideneacetic Acid Ethyl Ester; Acetic acid, 2-cyclopropylidene-, ethyl ester, (1E)-; Ethyl trans-2-Cyclopropylideneacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(1E)-Cyclopropylidene]Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (E/Z Ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.