Description

1-(2-Thienyl)-3-(3,4-Dimethoxyphenyl)-2-Propen-1-One is a high-purity, synthetic chalcone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of electron-transporting or emissive layers due to its conjugated molecular structure.
• Agrochemical Research: Serves as a scaffold for developing new fungicides or herbicides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Utilized as a core structure for designing molecular probes to study enzyme mechanisms or protein interactions.
• Material Science: Investigated for use in nonlinear optical (NLO) materials and as a monomer for specialized polymers.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including catalysis and green chemistry applications.

Basic Information

Product Name	1-(2-Thienyl)-3-(3,4-Dimethoxyphenyl)-2-Propen-1-One
CAS No.	74441-58-0
Molecular Formula	C₁₅H₁₄O₃S
Molecular Weight	274.33 g/mol
Synonyms	3,4-Dimethoxychalcone-2'-thienyl; 1-(Thiophen-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one; 2-Propen-1-one, 1-(2-thienyl)-3-(3,4-dimethoxyphenyl)-; (E)-1-(Thiophen-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one; 3',4'-Dimethoxy-2-thienylchalcone; 2-Thienyl-3,4-dimethoxychalcone; NSC 407296
EINECS	Contact for details

Quality Control

Our 1-(2-Thienyl)-3-(3,4-Dimethoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with your specified requirements. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.