Description

6-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-2,3,4,5-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime) is a highly specialized, multi-protected carbohydrate derivative designed for advanced synthetic chemistry. This compound is a critical protected glycosyl donor and key synthetic intermediate for constructing complex oligosaccharides and glycoconjugates with precise stereochemistry. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycotherapeutics, and in academic research focused on carbohydrate chemistry and chemical biology.

Application

• Glycosylation Reactions: Acts as a key building block for the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Serves as a critical precursor in the development of carbohydrate-based drugs, including antibiotics, antivirals, and anticancer agents.
• Glycoconjugate Synthesis: Used for the chemical preparation of glycoproteins, glycolipids, and other biologically active glycoconjugates for research and therapeutic applications.
• Chemical Biology Probes: Enables the synthesis of labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
• Process Development: Employed in the scale-up and optimization of synthetic routes for carbohydrate-active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A valuable tool for research in synthetic organic chemistry, medicinal chemistry, and glycoscience.

Basic Information

Item	Detail
Product Name	6-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-2,3,4,5-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime)
CAS No.	74421-41-3
Molecular Formula	C34H63NO8Si5
Molecular Weight	782.39 g/mol
Synonyms	1-(O-Methyloxime) of 6-O-[3-Acetyl-1-(trimethylsilyl)-1H-indol-1-yl]-2,3,4,5-tetra-O-(trimethylsilyl)-D-glucose; 6-O-(3-Acetyl-1-trimethylsilylindol-1-yl)-2,3,4,5-tetra-O-trimethylsilyl-D-glucose O-methyloxime; Protected D-Glucose Indole Derivative; TMS-protected Glycosyl Donor; Silylated Carbohydrate Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and cGMP manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This compound is moisture-sensitive and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.