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4-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-2,3,5,6-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime) CAS NO 74421-40-2


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CAS No.:74421-40-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-2,3,5,6-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime) is a sophisticated, multi-functionalized carbohydrate derivative designed for advanced synthetic chemistry. This compound is a key protected intermediate, offering significant value in the synthesis of complex glycoconjugates and bioactive molecules due to its multiple silyl protecting groups. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of new therapeutic agents and chemical probes.

Application

  • Advanced Glycoconjugate Synthesis: Serves as a critical, protected building block for the construction of complex oligosaccharides and glycopeptides.
  • Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in areas targeting carbohydrate-protein interactions.
  • Chemical Biology Probes: Enables the synthesis of labeled or modified sugars for studying biological recognition and metabolic pathways.
  • Process Chemistry Development: Provides a stable, versatile intermediate for scaling up synthetic routes in fine chemical and API manufacturing.
  • Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and carbohydrate chemistry.

Basic Information

Item Details
Product Name 4-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-2,3,5,6-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime)
CAS No. 74421-40-2
Molecular Formula C34H61NO8Si5
Molecular Weight 764.33 g/mol
Synonyms 1-(O-Methyloxime) of 4-O-[3-Acetyl-1-(trimethylsilyl)-1H-indol-1-yl]-2,3,5,6-tetra-O-(trimethylsilyl)-D-glucose; D-Glucose, 4-O-[3-acetyl-1-(trimethylsilyl)-1H-indol-1-yl]-2,3,5,6-tetra-O-(trimethylsilyl)-, 1-(O-methyloxime); Protected Glucose-Indole Conjugate; TMS-protected Glycosyl Donor; Silylated Carbohydrate Intermediate
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 4-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-2,3,5,6-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime) is characterized using advanced analytical techniques (NMR, HPLC, MS) to confirm identity and purity. Certificates of Analysis (COA) with detailed specifications are available upon request, supporting your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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