Description

Methyl (2E,6E,10E)-3,7,11,15-Tetramethyl-9-(Phenylsulfonyl)-2,6,10,14- Hexadecatetraenoate is a specialized synthetic intermediate featuring a conjugated tetraene backbone and a phenylsulfonyl functional group. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists working on novel therapeutic agents, advanced materials, and other high-value chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of retinoid analogs, vitamin A derivatives, and other biologically active compounds with polyene structures.
• Organic Synthesis Building Block: Utilized in coupling reactions, cycloadditions, and other transformations where the sulfonyl group acts as an activating or directing moiety.
• Medicinal Chemistry Research: Employed in drug discovery programs targeting nuclear receptors, enzymes, and other biological pathways modulated by polyene structures.
• Material Science Precursor: Investigated for the development of organic semiconductors, liquid crystals, or photoresponsive materials due to its extended conjugated system.
• Chemical Biology Probe Development: Used to create labeled or modified compounds for studying biological processes and protein interactions.

Basic Information

Product Name	Methyl (2E,6E,10E)-3,7,11,15-Tetramethyl-9-(Phenylsulfonyl)-2,6,10,14-Hexadecatetraenoate
CAS No.	74367-17-2
Molecular Formula	C27H38O4S
Molecular Weight	458.66 g/mol
Synonyms	Methyl 9-(Phenylsulfonyl)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenoate; (2E,6E,10E)-Methyl 3,7,11,15-tetramethyl-9-(phenylsulfonyl)-2,6,10,14-hexadecatetraenoate; 9-(Phenylsulfonyl)retinyl methyl ester; All-trans-9-(Phenylsulfonyl)retinoic acid methyl ester; Phenylsulfonyl retinyl ester
EINECS	Contact for details

Quality Control

Our Methyl (2E,6E,10E)-3,7,11,15-Tetramethyl-9-(Phenylsulfonyl)-2,6,10,14- Hexadecatetraenoate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay, isomeric purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
(2E,6E,10E)-Isomer Content	≥ 98.0% of total isomers
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.