Description

(3S)-Spiro[Cholestane-3,1'-Cyclobutan]-2'-One is a high-purity, steroidal spirocyclic compound characterized by its unique fused ring system. This specialized chemical intermediate is valued for its defined stereochemistry and rigid molecular framework, which are critical for advanced synthetic applications. It is primarily sought by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive molecules, complex natural product analogs, and materials science research.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new therapeutic agents, particularly for steroidal or hormone-related targets.
• Organic Synthesis Research: Used as a sophisticated starting material or intermediate in academic and industrial laboratories for constructing complex, polycyclic molecular architectures.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical analysis.
• Material Science Exploration: Investigated for potential use in the development of advanced organic materials, where its rigid spiro structure can impart specific physical properties.

Basic Information

Product Name	(3S)-Spiro[Cholestane-3,1'-Cyclobutan]-2'-One
CAS No.	74345-22-5
Molecular Formula	C₃₀H₅₀O
Molecular Weight	426.73 g/mol
Synonyms	(3S)-Spiro[cholestane-3,1'-cyclobutan]-2'-one; (3S)-2'-Spirocholestan-3-one; 2'H-Spiro[cholestane-3,1'-cyclobutan]-2'-one, (3S)-; (3S)-Spirocholestanone; Spiro[cholestane-3,1'-cyclobutan]-2'-one, (3S)-; 74345-22-5; (3S)-2'-Oxaspiro[cholestane-3,1'-cyclobutane]
EINECS	Contact for details

Quality Control

We supply (3S)-Spiro[Cholestane-3,1'-Cyclobutan]-2'-One to meet exacting research and development standards. Every batch is subjected to rigorous analytical characterization, including chromatographic purity analysis and structural confirmation, to ensure identity, potency, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.