Description

(13'ξ,14'ξ)-Spiro[Cyclobutane-1,16'-Estra[1,3,5,7,9]Penten]-2-One is a high-purity, structurally complex steroid derivative characterized by its unique spirocyclic framework. This compound matters as a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting hormone-related pathways. It is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable access to high-quality, specialized building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel steroid-based therapeutics.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct advanced molecular architectures for drug discovery.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new biological activities.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Utilized in studies investigating steroid receptor interactions and metabolic pathways.
• Process Chemistry Development: Applied in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(13'ξ,14'ξ)-Spiro[Cyclobutane-1,16'-Estra[1,3,5,7,9]Penten]-2-One
CAS No.	74310-23-9
Molecular Formula	C22H28O
Molecular Weight	308.46 g/mol
Synonyms	Spiro[cyclobutane-1,16'-estra[1,3,5,7,9]penten]-2-one, (13xi,14xi)-; 74310-23-9; (13xi,14xi)-Spiro[cyclobutane-1,16'-estra[1,3,5,7,9]penten]-2-one; Spiroestra derivative; Steroid spirocyclic ketone; Estrapentenone derivative; Advanced steroid intermediate
EINECS	Contact for details

Quality Control

Every batch of (13'ξ,14'ξ)-Spiro[Cyclobutane-1,16'-Estra[1,3,5,7,9]Penten]-2-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing. Our products are produced to meet the stringent requirements for pharmaceutical research intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.