Description

6α-Methyl-17,21-Bis[(Trimethylsilyl)Oxy]Pregn-4-Ene-3,20-Dione Bis(o-Methyl Oxime) is a high-purity, advanced pharmaceutical intermediate featuring protective trimethylsilyl (TMS) and oxime functional groups. This compound is critical for synthetic chemists in the pharmaceutical industry, offering a protected and reactive scaffold for the targeted synthesis of complex steroid derivatives. It is primarily utilized in research and development for creating novel active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new therapeutic steroid compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of steroid drugs.
• Academic Research: Utilized in university and institutional labs for studying steroid chemistry and reaction mechanisms.

Basic Information

Product Name	6α-Methyl-17,21-Bis[(Trimethylsilyl)Oxy]Pregn-4-Ene-3,20-Dione Bis(o-Methyl Oxime)
CAS No.	74299-03-9
Molecular Formula	C31H54N2O4Si2
Molecular Weight	574.94 g/mol
Synonyms	6α-Methyl-17α,21-bis[(trimethylsilyl)oxy]pregn-4-ene-3,20-dione dioxime; 6α-Methyl-17α,21-bis(trimethylsiloxy)pregn-4-ene-3,20-dione bis-O-methyloxime; Pregn-4-ene-3,20-dione, 6-methyl-17,21-bis[(trimethylsilyl)oxy]-, dioxime, (6α,17α)-; 74299-03-9; 6-Methyl-17,21-bis(trimethylsiloxy)pregn-4-ene-3,20-dione dioxime
EINECS	Contact for details

Quality Control

Our 6α-Methyl-17,21-Bis[(Trimethylsilyl)Oxy]Pregn-4-Ene-3,20-Dione Bis(o-Methyl Oxime) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.