Description

2-Propenoicacid,3-(3,4-Dihydroxyphenyl)-,Ethylester,(2Z)-(9Ci) is a specialized caffeic acid derivative, specifically the (Z)-isomer of caffeic acid ethyl ester. This compound matters for its role as a key synthetic intermediate and reference standard in pharmaceutical and nutraceutical research, particularly in studies related to antioxidant and anti-inflammatory activities. Industries that need it include fine chemical synthesis, academic and industrial R&D for drug discovery, and manufacturers of high-purity analytical standards. Its defined stereochemistry and purity are critical for reproducible biological and chemical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex bioactive molecules and potential drug candidates.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for quality control and method validation in laboratories.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate antioxidant, anti-inflammatory, and neuroprotective mechanisms.
• Nutraceutical Development: Acts as a model compound for developing and testing natural product-derived health supplements.
• Cosmetic Ingredient Research: Studied for potential application in skincare formulations targeting oxidative stress and aging.
• Organic Synthesis: Utilized in stereoselective synthesis and as a starting material for creating novel chemical libraries.

Basic Information

Product Name	2-Propenoicacid,3-(3,4-Dihydroxyphenyl)-,Ethylester,(2Z)-(9Ci)
CAS No.	74257-25-3
Molecular Formula	C11H12O4
Molecular Weight	208.21 g/mol
Synonyms	(Z)-Caffeic Acid Ethyl Ester; Ethyl (Z)-3-(3,4-Dihydroxyphenyl)acrylate; (2Z)-3-(3,4-Dihydroxyphenyl)-2-propenoic Acid Ethyl Ester; Caffeic Acid Ethyl Ester (Z-isomer); CAEE (Z-form); 3,4-Dihydroxycinnamic Acid Ethyl Ester (cis-); (Z)-Ethyl 3,4-dihydroxycinnamate
EINECS	Contact for details

Quality Control

Our production of 2-Propenoicacid,3-(3,4-Dihydroxyphenyl)-,Ethylester,(2Z)-(9Ci) adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity, essential for research and synthesis. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.