Description

(2R,3R)-Diethyl 2-Acetoxy-3-Bromosuccinate CAS NO 74213-59-5 is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions, including aldol condensations and Michael additions, to install defined stereocenters.
• Natural Product Synthesis: Serves as a building block for the total synthesis of natural products with intricate stereochemistry.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Catalyst and Ligand Development: Acts as a precursor for synthesizing novel chiral catalysts and ligands used in enantioselective catalysis.
• Academic & R&D Laboratories: Employed in methodological research for developing new synthetic routes and studying reaction mechanisms.

Basic Information

Product Name	(2R,3R)-Diethyl 2-Acetoxy-3-Bromosuccinate
CAS No.	74213-59-5
Molecular Formula	C10H15BrO6
Molecular Weight	311.13 g/mol
Synonyms	Diethyl (2R,3R)-2-(Acetyloxy)-3-bromobutanedioate; (2R,3R)-2-Acetoxy-3-bromosuccinic Acid Diethyl Ester; Diethyl 2-Acetoxy-3-bromosuccinate; Ethyl 2-Acetoxy-3-bromosuccinate; Bromosuccinic Acid Diethyl Ester Acetate; (2R,3R)-Diethyl O-Acetyl-3-bromomalate
EINECS	Contact for details

Quality Control

Our (2R,3R)-Diethyl 2-Acetoxy-3-Bromosuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.