Description

n-2,2,2-Trifluoroethyl-2-(3,4-Dihydroxyphenyl)Ethylamine is a specialized fluorinated catecholamine derivative, a key building block in advanced organic synthesis. This compound matters for its unique trifluoroethyl group, which can impart significant metabolic stability and alter physicochemical properties in target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of fluorinated drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of novel fluorinated drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, fluorinated pesticides and herbicides, where the trifluoroethyl moiety can enhance biological activity and environmental persistence.
• Biochemical Research: Serves as a precursor or reference standard in studies involving catecholamine analogs, enzyme inhibitors, and receptor binding assays.
• Material Science: Potential building block for specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Organic Synthesis: A versatile reagent for introducing the 2,2,2-trifluoroethylamine group into complex molecular architectures.

Basic Information

Product Name	n-2,2,2-Trifluoroethyl-2-(3,4-Dihydroxyphenyl)Ethylamine
CAS No.	74074-78-5
Molecular Formula	C10H12F3NO2
Molecular Weight	235.20 g/mol
Synonyms	2-(3,4-Dihydroxyphenyl)-N-(2,2,2-trifluoroethyl)ethan-1-amine; 1-(3,4-Dihydroxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]ethane; N-(2,2,2-Trifluoroethyl)dopamine; TFED; 2,2,2-Trifluoroethyl dopamine; N-Trifluoroethyldopamine; N-(2,2,2-Trifluoroethyl)-2-(3,4-dihydroxyphenyl)ethylamine
EINECS	Contact for details

Quality Control

Our n-2,2,2-Trifluoroethyl-2-(3,4-Dihydroxyphenyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to minimize potential oxidation of the catechol moiety.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.