Description

2-Pyrrolidinecarboxylic Acid, 1-Hydroxy-, 1,2-Dibromoethyl Ester, Benz Oate, L- is a specialized chiral organic compound that serves as a valuable synthetic intermediate and building block in advanced chemical synthesis. Its unique structure, featuring both a pyrrolidine core and halogenated ester groups, makes it a critical precursor for the development of complex molecules with specific stereochemistry. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where precise molecular architecture is paramount for creating active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for neurological and metabolic drugs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where specific stereochemistry influences biological activity.
• Asymmetric Catalysis: Employed as a ligand precursor or chiral auxiliary in catalytic processes to induce enantioselectivity.
• Peptidomimetic Research: Serves as a proline derivative in the design and synthesis of peptide analogs and enzyme inhibitors.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	2-Pyrrolidinecarboxylic Acid, 1-Hydroxy-, 1,2-Dibromoethyl Ester, Benz Oate, L-
CAS No.	74039-33-1
Molecular Formula	C14H15Br2NO4
Molecular Weight	421.08 g/mol
Synonyms	L-1-Hydroxypyrrolidine-2-carboxylic Acid 1,2-Dibromoethyl Ester Benzoate; (S)-1-Hydroxypyrrolidine-2-carboxylic Acid (2,2-Dibromoethoxy)carbonyl Benzoate; 1,2-Dibromoethyl (S)-1-Hydroxypyrrolidine-2-carboxylate Benzoate; N-Hydroxy-L-proline 1,2-Dibromoethyl Ester Benzoate; Dibromoethyl Ester of N-Hydroxy-L-proline Benzoate; 74039-33-1; L-Form N-Hydroxyproline Dibromoethyl Ester Benzoate
EINECS	Contact for details

Quality Control

Our production of 2-Pyrrolidinecarboxylic Acid, 1-Hydroxy-, 1,2-Dibromoethyl Ester, Benz Oate, L- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is subjected to comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) providing specifications for identity, assay, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.