Description

4,7-Epoxyoctahydro-2H-Isoindole-2-Carboxylic Acid Isopropyl Ester is a high-value, specialized chemical intermediate characterized by its unique bicyclic structure incorporating an epoxide and an ester functional group. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed as a functional monomer or cross-linking agent to introduce rigidity and specific reactivity into specialty polymers and resins.
• Fine Chemical Production: Acts as a building block for synthesizing complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable tool for methodological studies in organic synthesis, particularly in ring-opening and functionalization reactions.

Basic Information

Product Name	4,7-Epoxyoctahydro-2H-Isoindole-2-Carboxylic Acid Isopropyl Ester
CAS No.	73986-88-6
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	Isopropyl 4,7-epoxy-2,3,3a,4,7,7a-hexahydro-1H-isoindole-2-carboxylate; 1H-Isoindole-2-carboxylic acid, 4,7-epoxyhexahydro-, 1-methylethyl ester; 4,7-Epoxyhexahydro-1H-isoindole-2-carboxylic acid isopropyl ester; (3aR,4S,7R,7aS)-Isopropyl 4,7-epoxyhexahydro-1H-isoindole-2-carboxylate; (3aR,4S,7R,7aS)-4,7-Epoxyoctahydro-2H-isoindole-2-carboxylic acid 1-methylethyl ester; Isopropyl (3aR,4S,7R,7aS)-4,7-epoxyhexahydro-1H-isoindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4,7-Epoxyoctahydro-2H-Isoindole-2-Carboxylic Acid Isopropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting compliance in cGMP and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.