Description

1-α-H,5-α-H-Tropanium, 8-Butyl-3-Hydroxy-, Bromide, Benzilate is a specialized quaternary ammonium salt derivative of tropane, designed for high-value research and development applications. This compound matters for its potential as a key synthetic intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on neuropharmacology, medicinal chemistry, and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new drug candidates with anticholinergic or related properties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Process Development: Utilized in scaling up synthetic routes and optimizing manufacturing processes for related tropane alkaloid derivatives.
• Biochemical Research: Applied in in-vitro studies to investigate interactions with muscarinic acetylcholine receptors and other biological targets.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionalized molecules in advanced organic synthesis.

Basic Information

Product Name	1-α-H,5-α-H-Tropanium, 8-Butyl-3-Hydroxy-, Bromide, Benzilate
CAS No.	73954-05-9
Molecular Formula	C26H32BrNO4
Molecular Weight	502.45 g/mol
Synonyms	8-Butyl-3-hydroxy-1αH,5αH-tropanium bromide benzilate; 3-Hydroxy-8-butyl-1αH,5αH-tropanium bromide benzilate; Benzilic acid 8-butyl-3-hydroxy-1αH,5αH-tropanium bromide ester; Tropanium, 8-butyl-3-hydroxy-, bromide, benzilate (1αH,5αH)-; 73954-05-9; 8-Butyl-3-hydroxytropanium bromide benzilate
EINECS	Contact for details

Quality Control

Our 1-α-H,5-α-H-Tropanium, 8-Butyl-3-Hydroxy-, Bromide, Benzilate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.