Description

8-Ethynyl-8-Methyl-1,4-Dioxaspiro(4,5)-Dec-6-Ene is a high-value, specialized organic intermediate featuring a unique spirocyclic acetal structure combined with an alkynyl functional group. This compound matters as a versatile and critical building block for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring spirocyclic or constrained ring systems.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive alkyne for further functionalization.
• Ligand and Catalyst Development: The alkyne moiety allows for use in click chemistry and as a starting point for synthesizing specialized ligands in catalysis.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and ring-opening transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance or flavor molecules where structural precision is required.

Basic Information

Product Name	8-Ethynyl-8-Methyl-1,4-Dioxaspiro(4,5)-Dec-6-Ene
CAS No.	73843-26-2
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	8-Ethynyl-8-methyl-1,4-dioxaspiro[4.5]dec-6-ene; 8-Methyl-8-ethynyl-1,4-dioxaspiro[4.5]dec-6-ene; Spiro[1,3-dioxolane-2,1'-cyclohex-4'-ene], 5'-ethynyl-5'-methyl-; 5'-Ethynyl-5'-methylspiro[1,3-dioxolane-2,1'-cyclohex-4'-ene]; 73843-26-2; 8-Methyl-8-ethynyl-1,4-dioxaspiro[4.5]-6-decene
EINECS	Contact for details

Quality Control

Our 8-Ethynyl-8-Methyl-1,4-Dioxaspiro(4,5)-Dec-6-Ene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept tightly sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.