Description

tert-Butyl 6-Hydroxyhexanoate is a valuable bifunctional chemical intermediate featuring both a protected carboxylic acid and a free hydroxyl group. This unique structure makes it a versatile building block for the synthesis of more complex molecules, particularly in pharmaceutical and fine chemical manufacturing. It is essential for researchers and production chemists in the life sciences and specialty chemical sectors who require high-purity intermediates for API synthesis and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a hexanoic acid backbone with a protected terminus.
• Polymer Chemistry: Used as a monomer or chain modifier in the production of specialty polyesters and polyurethanes, influencing flexibility and hydrophilicity.
• Linker Molecule Synthesis: Employed in the creation of biodegradable linkers for drug delivery systems and prodrugs due to its ester and hydroxyl functionalities.
• Fine Chemical Synthesis: Serves as a precursor for fragrances, flavors, and other high-value organic compounds requiring specific carbon chain lengths.
• Material Science Research: Utilized in R&D for developing novel coatings, adhesives, and functional materials with tailored properties.
• Organic Synthesis Reagent: Acts as a protected form of 6-hydroxyhexanoic acid, allowing selective reactions at the hydroxyl group in multi-step syntheses.

Basic Information

Product Name	tert-Butyl 6-Hydroxyhexanoate
CAS No.	73839-20-0
Molecular Formula	C₁₀H₂₀O₃
Molecular Weight	188.26 g/mol
Synonyms	6-Hydroxyhexanoic Acid tert-Butyl Ester; tert-Butyl 6-Hydroxycaproate; 6-(tert-Butoxycarbonyloxy)hexanoic Acid (tautomeric form); 1,1-Dimethylethyl 6-Hydroxyhexanoate; Hexanoic acid, 6-hydroxy-, 1,1-dimethylethyl ester; TBHHA; t-Butyl 6-hydroxyhexanoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Hydroxyhexanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. The product is compatible with standard organic solvent storage conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.