Description

Ethyl Oxo-(4-Trifluoromethylphenyl)Acetate is a high-value fluorinated aromatic ester building block, essential for the synthesis of advanced chemical intermediates. Its core value lies in the unique reactivity of the oxoacetate moiety combined with the electron-withdrawing trifluoromethyl group, enabling precise molecular construction. This compound is critically needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a functionalized trifluoromethylphenyl group.

Basic Information

Product Name	Ethyl Oxo-(4-Trifluoromethylphenyl)Acetate
CAS No.	73790-06-4
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	Ethyl 2-oxo-2-[4-(trifluoromethyl)phenyl]acetate; Ethyl (4-Trifluoromethylphenyl)glyoxylate; 2-Oxo-2-[4-(trifluoromethyl)phenyl]acetic Acid Ethyl Ester; 4-(Trifluoromethyl)phenylglyoxylic Acid Ethyl Ester; α-Oxo-4-(trifluoromethyl)benzeneacetic Acid Ethyl Ester; Ethyl α-oxo-4-(trifluoromethyl)benzeneacetate; Ethyl (4-Trifluoromethylbenzoyl)formate
EINECS	Contact for details

Quality Control

Our Ethyl Oxo-(4-Trifluoromethylphenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.