Description

Acetamide, n-tert-Butyl-n-(1-Cyano-2-(3-Pyridyl)Amidino)-, Hydrate is a specialized organic compound with a complex molecular structure featuring acetamide, cyano, and pyridyl functional groups. This compound matters as a high-value chemical intermediate, offering a unique reactive scaffold for synthesizing advanced molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the development of novel active ingredients, as well as by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or as protease inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its amidino and pyridine motifs for biological activity.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and protein-ligand interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for introducing specific nitrogen-containing functional groups into complex architectures.
• Material Science Research: Potential monomer or precursor for synthesizing specialty polymers with specific ligand-binding properties.

Basic Information

Product Name	Acetamide, n-tert-Butyl-n-(1-Cyano-2-(3-Pyridyl)Amidino)-, Hydrate
CAS No.	73681-13-7
Molecular Formula	C₁₃H₁₉N₅O₂ (Hydrate form)
Molecular Weight	277.33 g/mol (Anhydrous basis)
Synonyms	N-tert-Butyl-N'-(1-cyano-2-(3-pyridinyl)amidino)acetamide hydrate; 1-Cyano-2-(3-pyridinyl)-N-(2,2-dimethylpropylidene)acetamidine hydrate; tert-Butyl N-cyano-N'-(3-pyridinyl)carbamimidoylacetamide hydrate; (1-Cyano-2-(pyridin-3-yl)guanidino)-tert-butyl ketone hydrate; 73681-13-7 (CAS Registry)
EINECS	Contact for details

Quality Control

Our Acetamide, n-tert-Butyl-n-(1-Cyano-2-(3-Pyridyl)Amidino)-, Hydrate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and KF titration for water content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.